FACTS ABOUT KETAMINE DOSE FOR PAIN REVEALED

Metabolism Ketamine is metabolized through N-dealkylation to your active metabolite norketamine largely by CYP2B6 and CYP3A4 also to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation on the cyclohexone ring to type hydroxynorketamine compounds by means of CYP-dependent pathways, which are conjugated with glucuronic acid and